The haemodynamic cascade

The haemodynamic cascade

In this issue of the Netherlands Heart Journal, Jansen et al. describe the influence stress echocardiography has on clinical decision-making in patients with mitral valve disease [1]. In 1935, Tenant and Wiggers described the sequelae of coronary occlusion [2]. From their description the ischaemic cascade has been derived. In this cascade, symptoms are a relatively late phenomenon and are prece...

The haemodynamic effects of morphine.

Modelling the haemodynamic response function

We present a method to extract the haemodynamic response function (HRF) from a functional magnetic resonance imaging (fMRI) time series. The method is based on Fourierwavelet regularised deconvolution (ForWaRD). The extraction algorithm is very general: it relies only on the assumptions of the general linear model (GLM) and the fact that signal and noise can be distinguished in the frequency an...

The haemodynamic effects of morphine.

I read with interest your editorial on the effects of morphine (Archives of Emergency Medicines 4, 131-132). I would agree that the benefits of treatment may not be due to any haemodynamic change produced. I would like to emphasize, however, that changes in blood pressure can occur after the administration of intravenous morphine and other opiates. Morphine has been shown to produce orthostatic...

The Haemodynamic Implications of the Bisferiens Pulse.

The indirect arterial pulse tracing from a healthy young person normally shows two systolic waves, the percussion wave and the tidal wave (Fig. 1). In hypertension and old age the percussion wave is usually small or absent (Fig. 2). In health, anwmia, and hyperthyroidism (Hancock and Abelmann, 1957), and in patent ductus arteriosus (Fig. 3), the two peaks may be prominent enough to give the pul...